Repurposing and computational design of PARP inhibitors as SARS-CoV-2 inhibitors

Abstract Coronavirus disease 2019 (COVID-19) is a recent pandemic that caused serious global emergency. To identify new and effective therapeutics, we employed a drug repurposing approach. The poly (ADP ribose) polymerase inhibitors were used for this purpose and were repurposed against the main pro...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Shailima Rampogu, Tae Sung Jung, Min Woo Ha, Keun Woo Lee
स्वरूप: लेख
भाषा:English
प्रकाशित: Nature Portfolio 2023-06-01
श्रृंखला:Scientific Reports
ऑनलाइन पहुंच:https://doi.org/10.1038/s41598-023-36342-7