Chronic Immune Platelet Activation Is Followed by Platelet Refractoriness and Impaired Contractility

Chronic Immune Platelet Activation Is Followed by Platelet Refractoriness and Impaired Contractility

Autoimmune diseases, including systemic lupus erythematosus (SLE), have a high risk of thrombotic and hemorrhagic complications associated with altered platelet functionality. We studied platelets from the blood of SLE patients and their reactivity. The surface expression of phosphatidylserine, P-se...

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Bibliographic Details
Main Authors: Izabella A. Andrianova, Alina I. Khabirova, Anastasia A. Ponomareva, Alina D. Peshkova, Natalia G. Evtugina, Giang Le Minh, Timur B. Sibgatullin, John W. Weisel, Rustem I. Litvinov
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
chronic immune inflammation
systemic lupus erythematosus
platelets
clot contraction
hemostatic disorders
Online Access:https://www.mdpi.com/1422-0067/23/13/7336

Internet

https://www.mdpi.com/1422-0067/23/13/7336

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