No contribution of GSTM1 and GSTT1 null genotypes to the risk of neutropenia due to benzene exposure in Southeastern Brazil

No contribution of GSTM1 and GSTT1 null genotypes to the risk of neutropenia due to benzene exposure in Southeastern Brazil

Exposure to benzene has been associated with haematological diseases such as neutropenia (NEB) and acute myeloid leukaemia (AML). We tested whether the null genotypes of the GSTM1 and GSTT1 genes, involved in benzene inactivation, altered the risk for NEB in southeastern Brazil. Genomic DNA from 55...

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Bibliographic Details
Main Authors: Carmen Silvia Passos Lima, Gustavo Jacob Lourenço, Irene Lorand-Metze, Helvia Nascimento, Sara Teresinha Ollala Saad, Fernando Ferreira Costa
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2009-01-01
Series:Genetics and Molecular Biology
Subjects:
neutropenia
glutathione S-transferase
GSTM1
GSTT1
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572009000400006

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572009000400006

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