Sensitive and reliable miRNA analysis based on cyclic reverse transcription and CRISPR-Cas12a-assisted signal cycle

Abstract MicroRNAs (miRNAs), a category of small molecules that possess significant regulatory capabilities, have been extensively employed as biomarkers in the domain of biosensing to facilitate the early detection of diverse ailments. However, sensitive and accurate miRNA detection remains a huge...

Full description

Bibliographic Details
Main Authors: Xiaoqing Yang, Jie Gao
Format: Article
Language:English
Published: SpringerOpen 2024-03-01
Series:Journal of Analytical Science and Technology
Subjects:
Online Access:https://doi.org/10.1186/s40543-024-00430-8