Impact of <i>CYP3A5</i>, <i>POR,</i> and <i>CYP2C19</i> Polymorphisms on Trough Concentration to Dose Ratio of Tacrolimus in Allogeneic Hematopoietic Stem Cell Transplantation
Single nucleotide polymorphisms in drug-metabolizing genes may affect tacrolimus pharmacokinetics. Here, we investigated the influence of genotypes of <i>CYP3A5</i>, <i>CYP2C19</i>, and <i>POR</i> on the concentration/dose (C/D) ratio of tacrolimus and episodes of...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-05-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/20/10/2413 |