Administration of olaquindox impairs spermatogenesis and sperm quality by increasing oxidative stress and early apoptosis in mice

Administration of olaquindox impairs spermatogenesis and sperm quality by increasing oxidative stress and early apoptosis in mice

Olaquindox (OLA), a potent antibacterial agent, has been widely used as a feed additive and growth promoter in animal husbandry. Our previous study has shown that OLA administration in female mice could markedly cause sub-fertility. Here we established the model in male mice to investigate the toxic...

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Bibliographic Details
Main Authors: Lei Ge, Yu-Qing Gao, Zhe Han, Shu-Jun Liu, Xing-Yue Wang, Xiao-Jie Zhang, Rui-Hao Tang, Rui-Feng Zhang, Dui Sun, Bo Feng, De-Jian Zhang, Cheng-Guang Liang
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Olaquindox
Testis
Sperm quality
Oxidative stress
Fertility
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322002366

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http://www.sciencedirect.com/science/article/pii/S0147651322002366

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