Strategy for Developing a Stable CHO Cell Line that Produces Large Titers of Trastuzumab Antibody

Background: Trastuzumab (Herceptin®) is currently the main treatment option for breast cancer patients that overexpress the human epidermal growth factor receptor 2 (HER2). This antibody binds specifically to HER2, blocks cancer cell growth, and promotes effective cell death. In the present study, w...

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Bibliographic Details
Main Authors: Hafsa Boulenouar, Nadia Bouchoutrouch, Youssef Amar, Moulay El Abbes Faouzi, Yahia Cherrah, Hassan Sefrioui, Hassan Ait Benhassou
Format: Article
Language:English
Published: IMR Press 2023-11-01
Series:Frontiers in Bioscience-Elite
Subjects:
Online Access:https://www.imrpress.com/journal/FBE/15/4/10.31083/j.fbe1504024