Altering Brain Amyloidosis by Intra-Lingual and Extra-Nasal Exposure of Aβ Aggregates

Altering Brain Amyloidosis by Intra-Lingual and Extra-Nasal Exposure of Aβ Aggregates

Extensive experimental and human-derived evidence suggest that misfolded Aβ particles spread similarly to infectious prions. Moreover, peripheral administration of Aβ seeds accelerates brain amyloidosis in both susceptible experimental animals and humans. The mechanisms and elements governing the tr...

Full description

Bibliographic Details
Main Authors: Nazaret Gamez, Javiera Bravo-Alegria, Yumeng Huang, Nelson Perez-Urrutia, Deepa Dongarwar, Claudio Soto, Rodrigo Morales
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cells
Subjects:
amyloid-beta
Alzheimer’s disease
prion
tongue
nasal cavity
Online Access:https://www.mdpi.com/2073-4409/11/21/3442

Internet

https://www.mdpi.com/2073-4409/11/21/3442

Similar Items