Autotaxin in Breast Cancer: Role, Epigenetic Regulation and Clinical Implications

Autotaxin in Breast Cancer: Role, Epigenetic Regulation and Clinical Implications

Autotaxin (ATX), the protein product of Ectonucleotide Pyrophosphatase Phosphodiesterase 2 (<i>ENPP2</i>), is a secreted lysophospholipase D (lysoPLD) responsible for the extracellular production of lysophosphatidic acid (LPA). ATX-LPA pathway signaling participates in several normal bio...

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Bibliographic Details
Main Authors: Andrianna Drosouni, Maria Panagopoulou, Vassilis Aidinis, Ekaterini Chatzaki
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cancers
Subjects:
autotaxin
<i>ENPP2</i>
lysophosphatidic acid
ATX-LPA signaling
expression
methylation
Online Access:https://www.mdpi.com/2072-6694/14/21/5437

Internet

https://www.mdpi.com/2072-6694/14/21/5437

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