Early-life exposure to PM2.5 leads to ASD-like phenotype in male offspring rats through activation of PI3K-AKT signaling pathway

Early-life exposure to PM2.5 leads to ASD-like phenotype in male offspring rats through activation of PI3K-AKT signaling pathway

Previous studies have shown that early-life exposure to fine particulate matter (PM2.5) is associated with an increasing risk of autism spectrum disorder (ASD), however, the specific sensitive period of ASD is unknown. Here, a model of dynamic whole-body concentrated PM2.5 exposure in pre- and early...

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Bibliographic Details
Main Authors: Kang Li, Xiaotian Liang, Xiaohua Liu, Yanpei Geng, Jun Yan, Lei Tian, Huanliang Liu, Wenqin Lai, Yue Shi, Zhuge Xi, Bencheng Lin
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Ecotoxicology and Environmental Safety
Subjects:
PM2.5
Autism spectrum disorder
Sensitive period
PTEN
PI3K-AKT signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324002987

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http://www.sciencedirect.com/science/article/pii/S0147651324002987

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