Technologies for High-Throughput Identification of Antibiotic Mechanism of Action

There are two main strategies for antibiotic discovery: target-based and phenotypic screening. The latter has been much more successful in delivering first-in-class antibiotics, despite the major bottleneck of delayed Mechanism-of-Action (MOA) identification. Although finding new antimicrobial compo...

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Bibliographic Details
Main Authors: Bernardo Ribeiro da Cunha, Paulo Zoio, Luís P. Fonseca, Cecília R. C. Calado
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/10/5/565