Knockdown of long non-coding RNA LEF1-AS1 attenuates apoptosis and inflammatory injury of microglia cells following spinal cord injury

Knockdown of long non-coding RNA LEF1-AS1 attenuates apoptosis and inflammatory injury of microglia cells following spinal cord injury

Abstract Background Spinal cord injury (SCI) is associated with health burden both at personal and societal levels. Recent assessments on the role of lncRNAs in SCI regulation have matured. Therefore, to comprehensively explore the function of lncRNA LEF1-AS1 in SCI, there is an urgent need to under...

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Bibliographic Details
Main Authors: Sheng-Yu Cui, Wei Zhang, Zhi-Ming Cui, Hong Yi, Da-Wei Xu, Wei Liu, Xin-Hui Zhu
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Spinal cord injury
LEF1-AS1
miR-222-5p
ceRNA
Inflammation
Apoptosis
Online Access:https://doi.org/10.1186/s13018-020-02041-6

Internet

https://doi.org/10.1186/s13018-020-02041-6

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