Efficient Removal of Non-Structural Protein Using Chloroform for Foot-and-Mouth Disease Vaccine Production

Efficient Removal of Non-Structural Protein Using Chloroform for Foot-and-Mouth Disease Vaccine Production

To differentiate foot-and-mouth disease (FMD)-infected animals from vaccinated livestock, non-structural proteins (NSPs) must be removed during the FMD vaccine manufacturing process. Currently, NSPs cannot be selectively removed from FMD virus (FMDV) culture supernatant. Therefore, polyethylene glyc...

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Bibliographic Details
Main Authors: Sun Young Park, Jung-Min Lee, Ah-Young Kim, Sang Hyun Park, Sim-In Lee, Hyejin Kim, Jae-Seok Kim, Jong-Hyeon Park, Young-Joon Ko, Choi-Kyu Park
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Vaccines
Subjects:
foot-and-mouth disease virus
inactivated vaccine
non-structural protein
purity
chloroform
Online Access:https://www.mdpi.com/2076-393X/8/3/483

Internet

https://www.mdpi.com/2076-393X/8/3/483

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