Redox Regulation of Microglial Inflammatory Response: Fine Control of NLRP3 Inflammasome through Nrf2 and NOX4

Redox Regulation of Microglial Inflammatory Response: Fine Control of NLRP3 Inflammasome through Nrf2 and NOX4

The role of inflammation and immunity in the pathomechanism of neurodegenerative diseases has become increasingly relevant within the past few years. In this context, the NOD-like receptor protein 3 (NLRP3) inflammasome plays a crucial role in the activation of inflammatory responses by promoting th...

Full description

Bibliographic Details
Main Authors: Alejandra Palomino-Antolín, Céline Decouty-Pérez, Víctor Farré-Alins, Paloma Narros-Fernández, Ana Belen Lopez-Rodriguez, María Álvarez-Rubal, Inés Valencia, Francisco López-Muñoz, Eva Ramos, Antonio Cuadrado, Ana I. Casas, Alejandro Romero, Javier Egea
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Antioxidants
Subjects:
inflammation and immunity
NLRP3 inflammasome
Nrf2
NOX4
glial cultures
KO mice
Online Access:https://www.mdpi.com/2076-3921/12/9/1729

Internet

https://www.mdpi.com/2076-3921/12/9/1729

Similar Items