Toxoplasma gondii soluble tachyzoite antigen triggers protective mechanisms against fatal intestinal pathology in oral infection of C57BL/6 mice.

Toxoplasma gondii soluble tachyzoite antigen triggers protective mechanisms against fatal intestinal pathology in oral infection of C57BL/6 mice.

Toxoplasma gondii induces a potent IL-12 response early in infection that results in IFN-γ-dependent control of parasite growth. It was previously shown that T. gondii soluble tachyzoite antigen (STAg) injected 48 hr before intraperitoneal infection reduces lipoxin A4 and 5-lipoxygenase (5-LO)-depen...

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Bibliographic Details
Main Authors: Luciana Benevides, Cristina R Cardoso, Cristiane M Milanezi, Letícia S Castro-Filice, Paulo V C Barenco, Romulo O Sousa, Rosangela M Rodrigues, José R Mineo, João S Silva, Neide M Silva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3782460?pdf=render

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http://europepmc.org/articles/PMC3782460?pdf=render

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