Self-Organized Liver Microtissue on a Bio-Functional Surface: The Role of Human Adipose-Derived Stromal Cells in Hepatic Function

Self-Organized Liver Microtissue on a Bio-Functional Surface: The Role of Human Adipose-Derived Stromal Cells in Hepatic Function

The maintenance of hepatocyte function is a critical research topic in liver tissue engineering. Although an increasing number of strategies have been developed, liver tissue engineering using hepatocytes as a therapeutic alternative remains challenging owing to its poor efficacy. In this study, we...

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Bibliographic Details
Main Authors: Seokheon Hong, Seung Ja Oh, Dongho Choi, Yongsung Hwang, Sang-Heon Kim
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
multicellular hepatic microtissue
human adipose stem cell
induced hepatocyte
hypoxia-inducible factor 1α
hepatocyte maturation
Online Access:https://www.mdpi.com/1422-0067/21/13/4605

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https://www.mdpi.com/1422-0067/21/13/4605

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