The mechano-electric feedback mediates the dual effect of stretch in mouse sinoatrial tissue
The sinoatrial node (SAN) is the primary heart pacemaker. The automaticity of SAN pacemaker cells is regulated by an integrated coupled-clock system. The beat interval (BI) of SAN, and its primary initiation location (inferior vs. superior) are determined by mutual entrainment among pacemaker cells...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-09-01
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Series: | Journal of Molecular and Cellular Cardiology Plus |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2772976123000120 |