Challenges and opportunities of bioprocessing 5-aminolevulinic acid using genetic and metabolic engineering: a critical review

Abstract 5-Aminolevulinic acid (5-ALA), a non-proteinogenic five-carbon amino acid, has received intensive attentions in medicine due to its approval by the US Food and Drug Administration (FDA) for cancer diagnosis and treatment as photodynamic therapy. As chemical synthesis of 5-ALA performed low...

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Bibliographic Details
Main Authors: Ying-Chen Yi, I-Tai Shih, Tzu-Hsuan Yu, Yen-Ju Lee, I-Son Ng
Format: Article
Language:English
Published: SpringerOpen 2021-10-01
Series:Bioresources and Bioprocessing
Subjects:
Online Access:https://doi.org/10.1186/s40643-021-00455-6