Adrenergic signalling to astrocytes in anterior cingulate cortex contributes to pain-related aversive memory in rats

Chemogenetic and optogenetic profiling in a rat model of acute pain-related unpleasantness suggests that colorectal distention-induced place aversion is mediated by locus coeruleus noradrenergic signalling to astrocytes in anterior cingulate cortex.

Bibliographic Details
Main Authors: Zafar Iqbal, Zhuogui Lei, Aruna S. Ramkrishnan, Shu Liu, Mahadi Hasan, Mastura Akter, Yuk Yan Lam, Ying Li
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-04405-6