Adrenergic signalling to astrocytes in anterior cingulate cortex contributes to pain-related aversive memory in rats
Chemogenetic and optogenetic profiling in a rat model of acute pain-related unpleasantness suggests that colorectal distention-induced place aversion is mediated by locus coeruleus noradrenergic signalling to astrocytes in anterior cingulate cortex.
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-01-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-04405-6 |
| _version_ | 1797958551128244224 |
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| author | Zafar Iqbal Zhuogui Lei Aruna S. Ramkrishnan Shu Liu Mahadi Hasan Mastura Akter Yuk Yan Lam Ying Li |
| author_facet | Zafar Iqbal Zhuogui Lei Aruna S. Ramkrishnan Shu Liu Mahadi Hasan Mastura Akter Yuk Yan Lam Ying Li |
| author_sort | Zafar Iqbal |
| collection | DOAJ |
| description | Chemogenetic and optogenetic profiling in a rat model of acute pain-related unpleasantness suggests that colorectal distention-induced place aversion is mediated by locus coeruleus noradrenergic signalling to astrocytes in anterior cingulate cortex. |
| first_indexed | 2024-04-11T00:20:39Z |
| format | Article |
| id | doaj.art-552ad68513c3411d840e0ac14412af7a |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-11T00:20:39Z |
| publishDate | 2023-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-552ad68513c3411d840e0ac14412af7a2023-01-08T12:18:38ZengNature PortfolioCommunications Biology2399-36422023-01-016111910.1038/s42003-022-04405-6Adrenergic signalling to astrocytes in anterior cingulate cortex contributes to pain-related aversive memory in ratsZafar Iqbal0Zhuogui Lei1Aruna S. Ramkrishnan2Shu Liu3Mahadi Hasan4Mastura Akter5Yuk Yan Lam6Ying Li7Department of Neuroscience, College of Veterinary Medicine and Life Sciences, City University of Hong KongDepartment of Neuroscience, College of Veterinary Medicine and Life Sciences, City University of Hong KongDepartment of Neuroscience, College of Veterinary Medicine and Life Sciences, City University of Hong KongDepartment of Neuroscience, College of Veterinary Medicine and Life Sciences, City University of Hong KongDepartment of Neuroscience, College of Veterinary Medicine and Life Sciences, City University of Hong KongDepartment of Neuroscience, College of Veterinary Medicine and Life Sciences, City University of Hong KongDepartment of Neuroscience, College of Veterinary Medicine and Life Sciences, City University of Hong KongDepartment of Neuroscience, College of Veterinary Medicine and Life Sciences, City University of Hong KongChemogenetic and optogenetic profiling in a rat model of acute pain-related unpleasantness suggests that colorectal distention-induced place aversion is mediated by locus coeruleus noradrenergic signalling to astrocytes in anterior cingulate cortex.https://doi.org/10.1038/s42003-022-04405-6 |
| spellingShingle | Zafar Iqbal Zhuogui Lei Aruna S. Ramkrishnan Shu Liu Mahadi Hasan Mastura Akter Yuk Yan Lam Ying Li Adrenergic signalling to astrocytes in anterior cingulate cortex contributes to pain-related aversive memory in rats Communications Biology |
| title | Adrenergic signalling to astrocytes in anterior cingulate cortex contributes to pain-related aversive memory in rats |
| title_full | Adrenergic signalling to astrocytes in anterior cingulate cortex contributes to pain-related aversive memory in rats |
| title_fullStr | Adrenergic signalling to astrocytes in anterior cingulate cortex contributes to pain-related aversive memory in rats |
| title_full_unstemmed | Adrenergic signalling to astrocytes in anterior cingulate cortex contributes to pain-related aversive memory in rats |
| title_short | Adrenergic signalling to astrocytes in anterior cingulate cortex contributes to pain-related aversive memory in rats |
| title_sort | adrenergic signalling to astrocytes in anterior cingulate cortex contributes to pain related aversive memory in rats |
| url | https://doi.org/10.1038/s42003-022-04405-6 |
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