Gestational Exposure to Cyfluthrin through Endoplasmic Reticulum (ER) Stress—Mediated PERK Signaling Pathway Impairs Placental Development

Gestational Exposure to Cyfluthrin through Endoplasmic Reticulum (ER) Stress—Mediated PERK Signaling Pathway Impairs Placental Development

Cyfluthrin, a typical type II pyrethroid pesticide, is widely used in house hygiene and agricultural pest control. Several epidemiological investigations have found that maternal pyrethroid exposure is connected to adverse pregnancy outcomes. However, the underlying mechanisms remain to be elucidate...

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Bibliographic Details
Main Authors: Wensi Ni, Haoxuan Gao, Bing Wu, Ji Zhao, Jian Sun, Yanan Song, Yiping Sun, Huifang Yang
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Toxics
Subjects:
cyfluthrin
gestational exposure
placental development
endoplasmic reticulum stress
PERK/eIF2α/ATF4/CHOP
Online Access:https://www.mdpi.com/2305-6304/10/12/733

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https://www.mdpi.com/2305-6304/10/12/733

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