Artificial Control of Subtype-Specific Platelet-Derived Growth Factor– Receptor Signaling

Platelet-derived growth factor (PDGF) signaling controls various physiological functions via two receptor subtypes: PDGF receptor (PDGFR) α and PDGFRβ. Nevertheless, our understanding of their roles is limited because of a lack of pharmacological tools to discriminate subtype-specific signaling. We...

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Bibliographic Details
Main Authors: Masayuki Isa, Yusaku Ohta, Shigeyuki Namiki, Kenzo Hirose
Format: Article
Language:English
Published: Elsevier 2009-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319310989