Anticonvulsant and ameliorative effects of pioglitazone on cognitive deficits, inflammation and apoptosis in the hippocampus of rat pups exposed to febrile seizure
Objective(s): Pioglitazone (PGZ), a peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist, has significant neuroprotective effects and has been reported to regulate inflammatory processes.Materials and Methods: We evaluated the effects of PGZ on febrile seizure (FS) in rat pups. Three gr...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Mashhad University of Medical Sciences
2019-03-01
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Series: | Iranian Journal of Basic Medical Sciences |
Subjects: | |
Online Access: | http://ijbms.mums.ac.ir/article_12195_0158855c3f687bdebb9ddaeb1c47e94a.pdf |