Mechanism of High-Level Daptomycin Resistance in <italic toggle="yes">Corynebacterium striatum</italic>

ABSTRACT Daptomycin, a last-line-of-defense antibiotic for treating Gram-positive infections, is experiencing clinical failure against important infectious agents, including Corynebacterium striatum. The recent transition of daptomycin to generic status is projected to dramatically increase availabi...

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Bibliographic Details
Main Authors: Nicholas K. Goldner, Christopher Bulow, Kevin Cho, Meghan Wallace, Fong-Fu Hsu, Gary J. Patti, Carey-Ann Burnham, Paul Schlesinger, Gautam Dantas
Format: Article
Language:English
Published: American Society for Microbiology 2018-08-01
Series:mSphere
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mSphereDirect.00371-18