Novel agents and evolving strategies in myelofibrotive neoplasm: an update from 2022 ASH annual conference

Abstract Myelofibrosis (MF) is a disorder characterized by the proliferation of myeloid precursors, commonly due to overactive JAK signaling. The discovery of the JAK2V617F mutation and subsequent development of JAK inhibitors (JAKi) results in reduced spleen size, improved symptom, and enhanced sur...

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Bibliographic Details
Main Authors: Andrew Wang, James Liu, Jeffrey J. Pu
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s13045-023-01446-0