Inhibition of NMDARs in the nucleus reticularis of the thalamus produces delta frequency bursting

Injection of NMDAR antagonist into the thalamus can produce delta frequency EEG oscillations in the thalamocortical system. It is surprising that an antagonist of an excitatory neurotransmitter should trigger such activity, and the mechanism is unknown. One hypothesis is that the antagonist blocks e...

Full description

Bibliographic Details
Main Authors: Yuchun Zhang, Rodolfo R Llinas, John Lisman
Format: Article
Language:English
Published: Frontiers Media S.A. 2009-11-01
Series:Frontiers in Neural Circuits
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/neuro.04.020.2009/full