Collagen Autoantibodies and Their Relationship to CCP Antibodies and Rheumatoid Factor in the Progression of Early Rheumatoid Arthritis

Serum autoantibodies to cyclic citrullinated peptides (anti-CCP) and rheumatoid factor (RF) are important markers for diagnosis and prognosis of rheumatoid arthritis (RA), but their autoantigens are not cartilage-specific. Autoantibodies to joint-specific type II collagen (CII) also occur in RA, and...

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Bibliographic Details
Main Authors: Senga F. Whittingham, Alex Stockman, Merrill J. Rowley
Format: Article
Language:English
Published: MDPI AG 2017-04-01
Series:Antibodies
Subjects:
Online Access:http://www.mdpi.com/2073-4468/6/2/6