Application of B cell immortalization for the isolation of antibodies and B cell clones from vaccine and infection settings

Application of B cell immortalization for the isolation of antibodies and B cell clones from vaccine and infection settings

The isolation and characterization of neutralizing antibodies from infection and vaccine settings informs future vaccine design, and methodologies that streamline the isolation of antibodies and the generation of B cell clones are of great interest. Retroviral transduction to express Bcl-6 and Bcl-x...

Full description

Bibliographic Details
Main Authors: Kristin L. Boswell, Timothy A. Watkins, Evan M. Cale, Jakob Samsel, Sarah F. Andrews, David R. Ambrozak, Jefferson I. Driscoll, Michael A. Messina, Sandeep Narpala, Christine S. Hopp, Alberto Cagigi, Joseph P. Casazza, Takuya Yamamoto, Tongqing Zhou, William R. Schief, Peter D. Crompton, Julie E. Ledgerwood, Mark Connors, Lucio Gama, Peter D. Kwong, Adrian McDermott, John R. Mascola, Richard A. Koup
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
B cell
immortalization
chronic infection
vaccination
malaria
HIV-1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1087018/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1087018/full

Similar Items