Soluble Semaphorin 4D Serum Concentrations Are Elevated in Critically Ill Patients with Liver Cirrhosis and Correlate with Aminotransferases

Soluble Semaphorin 4D Serum Concentrations Are Elevated in Critically Ill Patients with Liver Cirrhosis and Correlate with Aminotransferases

Semaphorin 4D (Sema4D), also known as CD100, is a multifunctional transmembrane protein with immunoregulatory functions. Upon the activation of immune cells, soluble Semaphorin 4D (sSema4D) is proteolytically cleaved from the membrane by metalloproteinases. sSema4D levels are elevated in various (au...

Full description

Bibliographic Details
Main Authors: Samira Abu Jhaisha, Philipp Hohlstein, Eray Yagmur, Vera Köller, Maike R. Pollmanns, Jule K. Adams, Theresa H. Wirtz, Jonathan F. Brozat, Lukas Bündgens, Karim Hamesch, Ralf Weiskirchen, Frank Tacke, Christian Trautwein, Alexander Koch
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Diagnostics
Subjects:
soluble Semaphorin 4D
sSema4D
sCD100
ICU
sepsis
prognosis
Online Access:https://www.mdpi.com/2075-4418/14/4/370

Internet

https://www.mdpi.com/2075-4418/14/4/370

Similar Items