Oxidative stress impairs energy metabolism in primary cells and synovial tissue of patients with rheumatoid arthritis

Abstract Background In this study, we examined the effect of oxidative stress on cellular energy metabolism and pro-angiogenic/pro-inflammatory mechanisms of primary rheumatoid arthritis synovial fibroblast cells (RASFC) and human umbilical vein endothelial cells (HUVEC). Methods Primary RASFC and H...

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Bibliographic Details
Main Authors: Emese Balogh, Douglas J. Veale, Trudy McGarry, Carl Orr, Zoltan Szekanecz, Chin-Teck Ng, Ursula Fearon, Monika Biniecka
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Arthritis Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13075-018-1592-1