A novel model of urosepsis in rats developed by injection of Escherichia coli into the renal pelvis

A novel model of urosepsis in rats developed by injection of Escherichia coli into the renal pelvis

Despite extensive research, urosepsis remains a life-threatening, high-mortality disease. Currently, animal models of urosepsis widely accepted by investigators are very scarce. This study aimed to establish a standardized and reproducible model of urosepsis in rats. Forty adult Wistar rats were ran...

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Bibliographic Details
Main Authors: Yuanfei Cao, Can Bai, Penghui Si, Xin Yan, Peng Zhang, Zuhaer Yisha, Peixiang Lu, Kuerban Tuoheti, Linfa Guo, Zhao Chen, Xiaojie Bai, Tongzu Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
urosepsis
rats
animal model
Escherichia coli
upper urinary tract obstruction
pathophysiology
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1074488/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1074488/full

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