Prenatal folic acid and vitamin B12 imbalance alter neuronal morphology and synaptic density in the mouse neocortex
Abstract Previous reports have provided evidence that insufficient or excessive maternal folic acid (FA) intake during pregnancy can alter neurodevelopment of the offspring by modulating prenatal neurogenesis. Furthermore, our earlier work in a mouse model confirmed long-term structural changes at t...
Main Authors: | Lyvin Tat, Noemi Cannizzaro, Zachary Schaaf, Shailaja Racherla, Teodoro Bottiglieri, Ralph Green, Konstantinos S. Zarbalis |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-11-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-023-05492-9 |
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