Repurposing <i>Astragalus</i> Polysaccharide PG2 for Inhibiting ACE2 and SARS-CoV-2 Spike Syncytial Formation and Anti-Inflammatory Effects

Repurposing <i>Astragalus</i> Polysaccharide PG2 for Inhibiting ACE2 and SARS-CoV-2 Spike Syncytial Formation and Anti-Inflammatory Effects

The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses a serious threat to global public health. In an effort to develop novel anti-coronavirus therapeutics and achieve prophylactics, we used gene set enrichment analysis (GSEA...

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Bibliographic Details
Main Authors: Chia-Yin Lee, Anh Thuc Nguyen, Ly Hien Doan, Li-Wei Chu, Chih-Hung Chang, Hui-Kang Liu, I-Lin Lee, Teng-Hsu Wang, Jin-Mei Lai, Shih-Ming Tsao, Hsiu-Jung Liao, Yueh-Hsin Ping, Chi-Ying F. Huang
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Viruses
Subjects:
COVID-19
microRNAs
macrophages
cytokine storm
viral entry
Online Access:https://www.mdpi.com/1999-4915/15/3/641

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https://www.mdpi.com/1999-4915/15/3/641

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