The nucleolus functions as the compartment for histone H2B protein degradation

Summary: Histones are main components of chromatin, and the protein levels of histones significantly affect chromatin assembly. However, how histone protein levels are regulated, especially whether and how histones are degraded, is largely unclear. Here, we found that histone H2B is mainly degraded...

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Bibliographic Details
Main Authors: Yanping Liu, Yufei Wang, Lu Yang, Feng Sun, Sheng Li, Yequan Wang, Guo-An Zhang, Tingting Dong, Lei-Lei Zhang, Wanglin Duan, Xiaojun Zhang, Wen Cui, Su Chen
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221002248