Iberverin exhibits antineoplastic activities against human hepatocellular carcinoma via DNA damage-mediated cell cycle arrest and mitochondrial-related apoptosis

Iberverin exhibits antineoplastic activities against human hepatocellular carcinoma via DNA damage-mediated cell cycle arrest and mitochondrial-related apoptosis

Hepatocellular carcinoma (HCC) is one of the malignant tumors with high incidence and mortality rates in the world. Isothiocyanates (ITCs), bioactive substances present primarily in the plant order Brassicales, have been proved to be promising candidates for novel anti-HCC drugs with chemopreventive...

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Bibliographic Details
Main Authors: Yuting Zhang, Jiao Du, Libo Jin, Liying Pan, Xiufeng Yan, Sue Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Pharmacology
Subjects:
hepatocellular carcinoma
iberverin
natural compound
antineoplastic activity
apoptosis
G2/M arrest
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1326346/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1326346/full

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