MST4 negatively regulates type I interferons production via targeting MAVS-mediated pathway

MST4 negatively regulates type I interferons production via targeting MAVS-mediated pathway

Abstract Background Cytosolic RNA sensing can elicit immune responses against viral pathogens. However, antiviral responses must be tightly regulated to avoid the uncontrolled production of type I interferons (IFN) that might have deleterious effects on the host. Upon bacterial infection, the germin...

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Bibliographic Details
Main Authors: Wei Liu, Zhenling Ma, Yaru Wu, Cui Yuan, Yanyan Zhang, Zeyang Liang, Yu Yang, Wenwen Zhang, Pengtao Jiao
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Cell Communication and Signaling
Subjects:
MST4
Innate immunity
RIG-I
Type I interferons
MAVS
Online Access:https://doi.org/10.1186/s12964-022-00922-3

Internet

https://doi.org/10.1186/s12964-022-00922-3

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