Circulating plasma IL-13 and periostin are dysregulated type 2 inflammatory biomarkers in prurigo nodularis: A cluster analysis

Circulating plasma IL-13 and periostin are dysregulated type 2 inflammatory biomarkers in prurigo nodularis: A cluster analysis

ImportancePrurigo nodularis (PN) is a chronic heterogeneous inflammatory skin disease.ObjectiveTo elucidate which components of type 2 inflammation are dysregulated systemically in PN.DesignWhole blood was obtained from PN patients with uncontrolled disease and control patients without pruritus. Pla...

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Bibliographic Details
Main Authors: Varsha Parthasarathy, Karen Cravero, Junwen Deng, Zhe Sun, Sarah M. Engle, Autum N. Auxier, Nathan Hahn, Jonathan T. Sims, Angela J. Okragly, Martin P. Alphonse, Shawn G. Kwatra
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Medicine
Subjects:
pruritus
itch
prurigo
inflammation
IL-13
Th2 (type-2) immune responses
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.1011142/full

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https://www.frontiersin.org/articles/10.3389/fmed.2022.1011142/full

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