Evaluation of an Engineered Zika Virus-Like Particle Vaccine Candidate in a Mosquito-Mouse Transmission Model

Evaluation of an Engineered Zika Virus-Like Particle Vaccine Candidate in a Mosquito-Mouse Transmission Model

ABSTRACT The primary route of Zika virus (ZIKV) transmission is through the bite of an infected Aedes mosquito, when it probes the skin of a vertebrate host during a blood meal. Viral particles are injected into the bite site together with mosquito saliva and a complex mixture of other components. S...

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Bibliographic Details
Main Authors: Maria Vittoria Mancini, Rapeepat Tandavanitj, Thomas H. Ant, Shivan M. Murdochy, Daniel D. Gingell, Chayanee Setthapramote, Piyatida Natsrita, Alain Kohl, Steven P. Sinkins, Arvind H. Patel, Giuditta De Lorenzo
Format: Article
Language:English
Published: American Society for Microbiology 2023-04-01
Series:mSphere
Subjects:
Aedes aegypti
arbovirus
flavivirus
mosquito
vaccine
Zika virus
Online Access:https://journals.asm.org/doi/10.1128/msphere.00564-22

Internet

https://journals.asm.org/doi/10.1128/msphere.00564-22

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