Intrahepatic cholangiocarcinoma induced M2-polarized tumor-associated macrophages facilitate tumor growth and invasiveness

Intrahepatic cholangiocarcinoma induced M2-polarized tumor-associated macrophages facilitate tumor growth and invasiveness

Abstract Background M2-polarized tumor-associated macrophages (M2-TAMs) have been shown to correlate with the progression of various cancers, including intrahepatic cholangiocarcinoma (ICC). However, the interactions and mechanism between M2 macrophages and ICC are not completely clear. We aimed to...

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Bibliographic Details
Main Authors: Hui Yuan, Zelong Lin, Yingjun Liu, Yuchuan Jiang, Ke Liu, Mengxian Tu, Nan Yao, Chen Qu, Jian Hong
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Cancer Cell International
Subjects:
Intrahepatic cholangiocarcinoma
M2 macrophage
Signal transducer and activator of transcription 3 (STAT3)
Epithelial–mesenchymal transition
Online Access:https://doi.org/10.1186/s12935-020-01687-w

Internet

https://doi.org/10.1186/s12935-020-01687-w

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