Simvastatin attenuates tibial bone loss in rats with type 1 diabetes and periodontitis

Simvastatin attenuates tibial bone loss in rats with type 1 diabetes and periodontitis

Abstract Background Diabetes induces long bone loss and aggravation of periodontitis-induced alveolar bone loss. Simvastatin (SIM), which is a lipid-lowering agent is known to have an anabolic effect on bone. Therefore, we investigated effect of SIM on tibial and alveolar bone loss in type 1 diabeti...

Full description

Bibliographic Details
Main Authors: Ae Ri Kim, Ji-Hye Kim, Aeryun Kim, Yongsung Sohn, Jeong-Heon Cha, Eun-Jung Bak, Yun-Jung Yoo
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Journal of Translational Medicine
Subjects:
Diabetes
Periodontitis
Bone loss
Sclerostin
Simvastatin
Online Access:http://link.springer.com/article/10.1186/s12967-018-1681-6

Internet

http://link.springer.com/article/10.1186/s12967-018-1681-6

Similar Items