The Hippo pathway component Wwc2 is a key regulator of embryonic development and angiogenesis in mice

The Hippo pathway component Wwc2 is a key regulator of embryonic development and angiogenesis in mice

Abstract The WW-and-C2-domain-containing (WWC) protein family is involved in the regulation of cell differentiation, cell proliferation, and organ growth control. As upstream components of the Hippo signaling pathway, WWC proteins activate the Large tumor suppressor (LATS) kinase that in turn phosph...

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Bibliographic Details
Main Authors: Anke Hermann, Guangming Wu, Pavel I. Nedvetsky, Viktoria C. Brücher, Charlotte Egbring, Jakob Bonse, Verena Höffken, Dirk Oliver Wennmann, Matthias Marks, Michael P. Krahn, Hans Schöler, Peter Heiduschka, Hermann Pavenstädt, Joachim Kremerskothen
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03409-0

Internet

https://doi.org/10.1038/s41419-021-03409-0

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