Differential impact of fentanyl and morphine doses on ticagrelor-induced platelet inhibition in ST-segment elevation myocardial infarction: a subgroup analysis from the PERSEUS randomized trial

Differential impact of fentanyl and morphine doses on ticagrelor-induced platelet inhibition in ST-segment elevation myocardial infarction: a subgroup analysis from the PERSEUS randomized trial

IntroductionAmong patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI), intravenous fentanyl does not enhance ticagrelor-induced platelet inhibition within 2 h compared to morphine. The impact of the total dose of fentanyl and...

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Bibliographic Details
Main Authors: Dorian Garin, Sophie Degrauwe, Federico Carbone, Yazan Musayeb, Nathalie Lauriers, Marco Valgimigli, Juan F. Iglesias
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
fentanyl
dose
pharmacodynamics
pharmacokinetics
ST-segment elevation myocardial infarction
ticagrelor
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2024.1324641/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2024.1324641/full

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