Novel common and rare genetic determinants of paraoxonase activity: FTO, SERPINA12, and ITGAL[S]

HDL-associated paraoxonase 1 (PON1) activity is associated with cardiovascular and other human diseases. As the role of genetic variants outside of the PON gene cluster on PON1 activity is unknown, we sought to identify common and rare variants in such loci. We typed 33,057 variants on the CVD chip...

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Bibliographic Details
Main Authors: Daniel S. Kim, Amber A. Burt, David R. Crosslin, Peggy D. Robertson, Jane E. Ranchalis, Edward J. Boyko, Deborah A. Nickerson, Clement E. Furlong, Gail P. Jarvik
Format: Article
Language:English
Published: Elsevier 2013-02-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520428202