Novel microwell-based spectrofluorimetric method assisted with fluorescence plate reader for determination of ruxolitinib: Optimization by response surface methodology and application to in-vitro drug release, content uniformity testing and analysis of u…

ABSTRACT: This study describes, for the first time, the development and validation of a novel microwell-based spectrofluorimetric method assisted with fluorescence plate reader (MWP-SFL) for determination of ruxolitinib (RUX), a drug approved for the treatment of moderate or high-risk myelofibrosis...

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Bibliographic Details
Main Authors: Abdullah M. Al-Hossaini, Abdullah S. Al-Mutairi, Ibrahim A. Darwish, Ahmed H. Bacheit, Awadh M Ali, Hany W. Darwish
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Talanta Open
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666831923000280