Infection-Induced Changes Within the Endocytic Recycling Compartment Suggest a Roadmap of Human Cytomegalovirus Egress

Infection-Induced Changes Within the Endocytic Recycling Compartment Suggest a Roadmap of Human Cytomegalovirus Egress

Human cytomegalovirus (HCMV) is an important pathogen in developing fetuses, neonates, and individuals with compromised immune systems. Gaps in our understanding of the mechanisms required for virion assembly stand in the way of development of antivirals targeting late stages of viral replication. D...

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Bibliographic Details
Main Authors: William L. Close, James E. Glassbrook, Stephen J. Gurczynski, Philip E. Pellett
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Microbiology
Subjects:
human cytomegalovirus
virion envelopment and egress
virion maturation
endosecretory system
herpesvirus envelopment and egress
virus–host interactions
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01888/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.01888/full

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