Differential Histone Distribution Patterns in Induced Asymmetrically Dividing Mouse Embryonic Stem Cells

Differential Histone Distribution Patterns in Induced Asymmetrically Dividing Mouse Embryonic Stem Cells

Summary: Wnt3a-coated beads can induce asymmetric divisions of mouse embryonic stem cells (mESCs), resulting in one self-renewed mESC and one differentiating epiblast stem cell. This provides an opportunity for studying histone inheritance pattern at a single-cell resolution in cell culture. Here, w...

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Bibliographic Details
Main Authors: Binbin Ma, Tung-Jui Trieu, Ji Cheng, Shuang Zhou, Qingsong Tang, Jing Xie, Ji-Long Liu, Keji Zhao, Shukry J. Habib, Xin Chen
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Cell Reports
Subjects:
histone
asymmetric cell division
mouse embryonic stem cells
Wnt3a beads
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720309888

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http://www.sciencedirect.com/science/article/pii/S2211124720309888

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