Differential Histone Distribution Patterns in Induced Asymmetrically Dividing Mouse Embryonic Stem Cells
Summary: Wnt3a-coated beads can induce asymmetric divisions of mouse embryonic stem cells (mESCs), resulting in one self-renewed mESC and one differentiating epiblast stem cell. This provides an opportunity for studying histone inheritance pattern at a single-cell resolution in cell culture. Here, w...
Main Authors: | Binbin Ma, Tung-Jui Trieu, Ji Cheng, Shuang Zhou, Qingsong Tang, Jing Xie, Ji-Long Liu, Keji Zhao, Shukry J. Habib, Xin Chen |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-08-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124720309888 |
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