Validation of a Psychosocial Chronic Stress Model in the Pig Using a Multidisciplinary Approach at the Gut-Brain and Behavior Levels

Validation of a Psychosocial Chronic Stress Model in the Pig Using a Multidisciplinary Approach at the Gut-Brain and Behavior Levels

Psychological chronic stress is an important risk factor for major depressive disorder, of which consequences have been widely studied in rodent models. This work aimed at describing a pig model of chronic stress based on social isolation, environmental impoverishment and unpredictability. Three gro...

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Bibliographic Details
Main Authors: Sophie Menneson, Samuel Ménicot, Stéphanie Ferret-Bernard, Sylvie Guérin, Véronique Romé, Laurence Le Normand, Gwénaëlle Randuineau, Giulio Gambarota, Virginie Noirot, Pierre Etienne, Nicolas Coquery, David Val-Laillet
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
depression
antidepressant
behavior
neuroimaging
monoamines
neurogenesis
Online Access:https://www.frontiersin.org/article/10.3389/fnbeh.2019.00161/full

Internet

https://www.frontiersin.org/article/10.3389/fnbeh.2019.00161/full

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