Tau accumulation in autosomal dominant Alzheimer’s disease: a longitudinal [18F]flortaucipir study

Abstract Cortical tau accumulation is a key pathological event that partly defines Alzheimer’s disease (AD) onset and is associated with cognitive decline and future disease progression. However, an improved understanding of the timing and pattern of early tau deposition in AD and how this may be tr...

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Bibliographic Details
Main Authors: Antoinette O’Connor, David M. Cash, Teresa Poole, Pawel J. Markiewicz, Maggie R. Fraser, Ian B. Malone, Jieqing Jiao, Philip S. J. Weston, Shaney Flores, Russ Hornbeck, Eric McDade, Michael Schöll, Brian A. Gordon, Randall J. Bateman, Tammie L. S. Benzinger, Nick C. Fox
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Alzheimer’s Research & Therapy
Online Access:https://doi.org/10.1186/s13195-023-01234-5