Sesquiterpene lactones from Artemisia vulgaris L. as potential NO inhibitors in LPS-induced RAW264.7 macrophage cells

Sesquiterpene lactones from Artemisia vulgaris L. as potential NO inhibitors in LPS-induced RAW264.7 macrophage cells

Twelve new guaianolide sesquiterpene lactones (1–12), along with ten known analogs (13–22) were isolated from an EtOH extract of the dried aerial parts of Artemisia vulgaris L. The new structures were elucidated via abundant spectroscopic data analyses (HRESIMS, IR, 1D, and 2D NMR), and the absolute...

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Bibliographic Details
Main Authors: Xiang-Yu Chen, Tao Liu, Yu-Ze Hu, Tian-Tian Qiao, Xiu-Juan Wu, Ping-Hua Sun, Chui-Wen Qian, Zhe Ren, Jun-Xia Zheng, Yi-Fei Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Chemistry
Subjects:
Artemisia vulgaris L.
new structures
guaianolide sesquiterpene lactones
anti-inflammatory
in silico
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2022.948714/full

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https://www.frontiersin.org/articles/10.3389/fchem.2022.948714/full

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